SIMAP - Similarity Matrix of Proteins

	Similarity Matrix of Proteins
	Today, protein sequence comparison is the most powerful tool in computational biology for characterizing protein sequences because of the enormous amount of information that is preserved throughout the evolutionary process. SIMAP is a public database of pre-calculated protein similarities that plays a key role in many bioinformatics methods. It contains about all currently published protein sequences and is continuously updated. The computational effort for keeping SIMAP up-to-date is constantly increasing. Please help to update SIMAP by calculating protein similarities on your computer. The computing power you donate supports manifold biological research projects that make use of SIMAP data.

About SIMAP - Similarity Matrix of Proteins

Join SIMAP - Similarity Matrix of Proteins

Read our rules and policies
Check the system requirements
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Create your account
Download, install and run the BOINC software. When prompted, enter the URL http://boinc.bio.wzw.tum.de/boincsimap
If having an old (non-SSE) CPU or running UNIX: download the SIMAP and HMMER applications

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Project status
Calculation of SIMAP updates is currently running.
The current workunits calculate the similarities and domains of approx. 260.000 new sequences from public databases imported in March 2009.
After these calculations are finished, next workunits are expected around May 1st.

Software status
PCs with SSE support (all modern PCs and notebooks):
simap 5.10 for Windows stable
simap 5.11 for Linux stable
hmmer 5.09 for Windows stable
hmmer 5.09 for Linux stable
PowerPC/Intel based Apple computers (Mac's):
simap 5.10 for MacOS >=10.3.9 stable
hmmer 5.09 for MacOS >=10.3.9 stable
PCs without SSE (e.g. PII, K6, early Athlons):
i386-simap** 5.10 for Windows stable
i386-simap** 5.11 for Linux stable
PC/PARISC/IA64/Alpha/Sparc platforms for UNIX:
UNIX simap** 5.10 stable
UNIX hmmer** 5.09 stable

** These applications need manual installation.

Server status
Web server: ok
File server: ok
Database server: ok

User of the day

lutab
Hello, We\'re an aerospace consultancy firm. We built an XBOX cluster just for fun, and we like to keep it busy. Hence we joined this project.

News (Deutsche Übersetzung)

VIRUS founded in some March new Workunits
April 01, 2009
A virus was detected in some new Workunits: the virus, called "AprilFish" by his creator on march 2005 (this is why we thought was innoque), attacks GPU-CPU BOINC com-lines causing CPU com overtiming and almost immediate crash. We are pretty sure this virus doesn't damage host's HW if no GPU is used for BOINC calculations. We apologize for this but our search must go ahead.
New Workunits in the evening (UTC) of March 31
March 30, 2009
New Workunits: the calculation of similarities and features of approx. 260.000 new sequences, that were imported from protein databases into SIMAP in March, will start in the evening (UTC) of March 31st.
...more

News is available as an RSS feed.

Technical News

November 29, 2007
Server downtime: This morning we had a downtime of our servers for several hours due to technical maintenance.

September 5, 2007
Key validation error: This morning we had a key validation error causing failed downloads of new results. After fixing this error, the server is running again. For calculated results of five aborted workunits we have granted the credits manually.
...more

http://boinc.bio.wzw.tum.de/boincsimap_cgi/cgi